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Protein Actions

Protein Actions PDF Author: Ken Dill
Publisher: Garland Science
ISBN: 1351815008
Category : Medical
Languages : en
Pages :

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Book Description
Protein Actions: Principles and Modeling is aimed at graduates, advanced undergraduates, and any professional who seeks an introduction to the biological, chemical, and physical properties of proteins. Broadly accessible to biophysicists and biochemists, it will be particularly useful to student and professional structural biologists and molecular biophysicists, bioinformaticians and computational biologists, biological chemists (particularly drug designers) and molecular bioengineers. The book begins by introducing the basic principles of protein structure and function. Some readers will be familiar with aspects of this, but the authors build up a more quantitative approach than their competitors. Emphasizing concepts and theory rather than experimental techniques, the book shows how proteins can be analyzed using the disciplines of elementary statistical mechanics, energetics, and kinetics. These chapters illuminate how proteins attain biologically active states and the properties of those states. The book ends with a synopsis the roles of computational biology and bioinformatics in protein science.

Protein Actions

Protein Actions PDF Author: Ken Dill
Publisher: Garland Science
ISBN: 1351815008
Category : Medical
Languages : en
Pages :

View

Book Description
Protein Actions: Principles and Modeling is aimed at graduates, advanced undergraduates, and any professional who seeks an introduction to the biological, chemical, and physical properties of proteins. Broadly accessible to biophysicists and biochemists, it will be particularly useful to student and professional structural biologists and molecular biophysicists, bioinformaticians and computational biologists, biological chemists (particularly drug designers) and molecular bioengineers. The book begins by introducing the basic principles of protein structure and function. Some readers will be familiar with aspects of this, but the authors build up a more quantitative approach than their competitors. Emphasizing concepts and theory rather than experimental techniques, the book shows how proteins can be analyzed using the disciplines of elementary statistical mechanics, energetics, and kinetics. These chapters illuminate how proteins attain biologically active states and the properties of those states. The book ends with a synopsis the roles of computational biology and bioinformatics in protein science.

Structure and Action of Molecular Chaperones

Structure and Action of Molecular Chaperones PDF Author: Lila M Gierasch
Publisher: World Scientific
ISBN: 9814749346
Category : Science
Languages : en
Pages :

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Book Description
This unique volume reviews the beautiful architectures and varying mechanical actions of the set of specialized cellular proteins called molecular chaperones, which provide essential kinetic assistance to processes of protein folding and unfolding in the cell. Ranging from multisubunit ring-shaped chaperonin and Hsp100 machines that use their central cavities to bind and compartmentalize action on proteins, to machines that use other topologies of recognition — binding cellular proteins in an archway or at the surface of a "clamp" or at the surface of a globular assembly — the structures show us the ways and means the cell has devised to assist its major effectors, proteins, to reach and maintain their unique active forms, as well as, when required, to disrupt protein structure in order to remodel or degrade. Each type of chaperone is beautifully illustrated by X-ray and EM structure determinations at near- atomic level resolution and described by a leader in the study of the respective family. The beauty of what Mother Nature has devised to accomplish essential assisting actions for proteins in vivo is fully appreciable.

Genes in Action

Genes in Action PDF Author: Upjohn Company
Publisher:
ISBN:
Category : Chromosomes
Languages : en
Pages : 44

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Book Description


Neurotoxicology, Third Edition

Neurotoxicology, Third Edition PDF Author: G. Jean Harry
Publisher: CRC Press
ISBN: 1420054880
Category : Medical
Languages : en
Pages : 334

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Book Description
This new edition presents an integrated approach to neurotoxicology, the study of organisms’ responses to changes in their environment and how interruption of the flow of information by chemical exposure causes a wide range of effects – from learning deficits, sensory disturbances in the extremities, and muscle weakness to seizures and signs similar to neurodegenerative disorders such as Parkinson’s or Alzheimer’s disease. It is an essential resource for understanding the sites and mechanisms of neurotoxicity, for formulating testable hypotheses about the effects of neurotoxicants, and for improving the risk assessment process.

Costanzo Physiology E-Book

Costanzo Physiology E-Book PDF Author: Linda S. Costanzo
Publisher: Elsevier Health Sciences
ISBN: 0323793363
Category : Medical
Languages : en
Pages : 528

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Book Description
Through six highly regarded editions, students and instructors alike have come to appreciate Dr. Linda Costanzo’s clear, helpful writing style, logical organization, and easy-to-follow presentation of a challenging and complex topic in medical education. Costanzo Physiology, 7th Edition, retains the step-by-step, to-the-point approach that makes this text ideal for coursework and USMLE preparation. Complex concepts are presented in a simple, easy-to-digest manner, and are accompanied by well-designed figures and tables that provide handy visuals for procedures or physiologic equations. Fully updated throughout, this edition remains the students’ choice for concise, clear instruction and a strong foundation in human physiology. Offers a comprehensive and consistent overview of core physiologic concepts at the organ system and cellular levels, making complex principles easy to understand. Presents information in a short, simple, and focused manner – the perfect presentation for success in coursework and on exams. Provides step-by-step explanations and easy-to-follow diagrams clearly depicting physiologic principles. Contains new coverage of SARS CoV-2 physiology, renal handling of uric acid, delta/delta analysis is acid-base physiology, endolymph physiology, respiratory distress syndrome, compensatory bronchiolar constriction, and more. Includes high-yield online features such as student FAQs with thorough explanations, animations, and video tutorials from Dr. Costanzo. Integrates equations and sample problems throughout the text. Features chapter summaries for quick overviews of important points, boxed Clinical Physiology Cases for a more thorough understanding of application, and end-of-chapter questions to reinforce understanding and retention. Evolve Instructor site with an image bank is available to instructors through their Elsevier sales rep or via request at https://evolve.elsevier.com.

The Wondrous Story of Anesthesia

The Wondrous Story of Anesthesia PDF Author: Edmond I Eger II
Publisher: Springer Science & Business Media
ISBN: 1461484413
Category : Medical
Languages : en
Pages : 944

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Book Description
Edited and written by an international "who's who" of more than 100 authors, including anesthesiologists, nurse anesthetists, bench scientists, a surgeon, and representatives of industry, this text provides a comprehensive history of anesthesia, unique in its focus on the people and events that shaped the specialty around the world, particularly during the past 70 years when anesthesia emerged from empiricism and developed into a science-based practice.

Current Topics

Current Topics PDF Author: William L. McGuire
Publisher: Springer
ISBN: 1489926631
Category : Medical
Languages : en
Pages : 271

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Book Description
Breast cancer continues to be a major problem. In Volume 1 of this series we dealt exclusively with topics concerned with therapy. In Volume 2 we explored various aspects of experimental biology which are critical to our developing better methods of diagnosis and treatment. In the pres ent volume, we tum to a series of individual topics of considerable interest, including systemic methods for hormonal ablation, screening for early cancer, male breast cancer, and more. The first chapter addresses the question of why some breast tumors metastasize and others do not. Based on elegant animal tumor models, Kim believes that metastasizing tumor cells are the undesirable by product of the host immune surveillance mechanism. Unstable mem brane structures lead to shedding of membrane constituents, abnormal locomotive properties, and evasion of the host defense system. Factors which alter membrane structure will therefore have to be considered in our approach to the management of early breast cancer.

Protein Kinase C in Insulin Action, Resistance, and Secretion

Protein Kinase C in Insulin Action, Resistance, and Secretion PDF Author: Robert V. Farese
Publisher: R G Landes Company
ISBN:
Category : Medical
Languages : en
Pages : 109

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Book Description


Essential Endocrinology and Diabetes

Essential Endocrinology and Diabetes PDF Author: Richard I. G. Holt
Publisher: John Wiley & Sons
ISBN: 1118764129
Category : Medical
Languages : en
Pages : 336

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Book Description
ESSENTIAL ENDOCRINOLOGY AND DIABETES The Essentials are an international, best-selling series of textbooks, all of which are designed to support lecture series or themes on core topics within the health sciences. See www.wiley.com for further details. Essential Endocrinology and Diabetes provides the accurate and up-to-date knowledge required for treating all areas of endocrinology and diabetes, covering the latest research, clinical guidelines, investigational methods, and therapies. This classic text explains the vital aspects of endocrine physiology in a succinct and easy-to-use format, with full-colour illustrations, clinical images, and case studies to assist readers in applying theory to practice. The text covers the principles of endocrinology, clinical endocrinology, and clinical diabetes and obesity, and has been revised throughout to present the most recent developments in the field. The seventh edition includes new and updated material on the latest molecular techniques, approaches to clinical investigation and diagnostics, next generation sequencing technology, and positron emission tomography (PET). The treatment of type 1 diabetes and type 2 diabetes has been updated with clinical algorithms and reflects significant advances such as incretin-based therapies, SGLT2 inhibitors, the development of better insulins, and technologies that support self-management. Provides students and practitioners with comprehensive and authoritative information on all major aspects of endocrine physiology Covers diagnosis, management, and complications of clinical disorders such as endocrine neoplasia, and type 1 diabetes and type 2 diabetes Explains the core principle of feedback regulation, which is vital for the correct interpretation of many clinical tests Features case histories, learning objectives, ‘recap’ links to chapter content, cross-referencing guides, key information boxes, and chapter summaries Essential Endocrinology and Diabetes, Seventh Edition is the ideal textbook for medical and biomedical students, junior doctors, and clinicians looking to refresh their knowledge of endocrine science. For more information on the complete range of Wiley medical student and junior doctor publishing, please visit: www.wiley.com To receive automatic updates on Wiley books and journals, join our email list. Sign up today at www.wiley.com/email All content reviewed by students for students Wiley Medical Education books are designed exactly for their intended audience. All of our books are developed in collaboration with students. This means that our books are always published with you, the student, in mind. If you would like to be one of our student reviewers, go to www.reviewmedicalbooks.com to find out more. This title is also available as an e-book. For more details, please see www.wiley.com/buy/9781118763964

FDA Consumer

FDA Consumer PDF Author:
Publisher:
ISBN:
Category : Consumer protection
Languages : en
Pages :

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Book Description