Cellular Organelles and the Extracellular Matrix

Cellular Organelles and the Extracellular Matrix PDF Author: Edward Bittar
Publisher: Elsevier
ISBN: 9780080531496
Category : Science
Languages : en
Pages : 292

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Book Description
This volume is in two parts. The first contains the remaining chapters on cellular organelles and several chapters relating to organelle disorders. An account of mitochondriopathis is given in the chapter on the mitochondrion rather than in a separate one. The subject matter of this part of the volume shows quite clearly that the interdisciplinary approach to the study of organelles has shed considerable light on the nature of the mechanisms underlying the etiology and pathobiology of many of these disorders. As an example, mutations in the genes encoding integral membrane proteins are found to lead to disturbances in peroxisome assembly. It is also interesting and significant that mistargeting of protein is now thought to be another cause. It will be revealing to see whether mistargeting is the result of mutations in the genes encoding chaperones. The second part of the volume is concerned with the extracellular matrix. It sets out to show that a vast body of new knowledge of the extracellular matrix is available to us. Take for example the integrin family of cell adhesion receptors. It turns out that integrins play a key role not only in adhesion but also in coupling signals to the nucleus via the cytoskeleton. As for fibronectins, they seem to link the matrix with the cytoskeleton by interacting with integrins. Collagen molecules are dealt with in the last two chapters. The boundaries of collagen in disease are defined by drawing a clear line of demarcation between systemic connective tissue disorders (e.g., scleroderma), better known as autoimmune diseases, and the heritable, and the heritable diseases such as osteogenesis imperfect and the Marfan syndrome. This classification takes into account a second group of acquired disorders of collagen forming tissues in which regional fibrosis is the hallmark. Liver cirrhosis and pulmonary fibrosis are prime examples. The decision to place Volumes 2 and 3 before those dealing with cell chemistry was not easily made. It was based on the view that most students will have had an undergraduate course in biochemistry of cell biology or both courses, and that they could go to Volumes 4-7 in which the subject of cell chemistry is covered, and then return to Volumes 2 and 3.

Plant Biotechnology, Volume 2

Plant Biotechnology, Volume 2 PDF Author: Sangita Sahni
Publisher: CRC Press
ISBN: 135181947X
Category : Science
Languages : en
Pages : 586

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Book Description
This volume is the second of the new two-volume Plant Biotechnology set. This volume covers many recent advances in the development of transgenic plants that have revolutionized our concepts of sustainable food production, cost-effective alternative energy strategies, microbial biofertilizers and biopesticides, and disease diagnostics through plant biotechnology. With the advancements in plant biotechnology, many of the customary approaches are out of date, and an understanding of new updated approaches is needed. This volume presents information related to recent methods of genetic transformation, gene silencing, development of transgenic crops, biosafety issues, microbial biotechnology, oxidative stress, and plant disease diagnostics and management. Key features: Provides an in-depth knowledge of various techniques of genetic transformation of plants, chloroplast, and fungus Describes advances in gene silencing in plants Discusses transgenic plants for various traits and their application in crop improvement Looks at genetically modified foods and biodiesel production Describes biotechnological approaches in horticultural and ornamental plants Explores the biosafety aspect associated with transgenic crops Considers the role of microbes in sustainable agriculture

Cellular Organelles

Cellular Organelles PDF Author: Edward Bittar
Publisher: Elsevier
ISBN: 9780080528793
Category : Science
Languages : en
Pages : 287

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Book Description
The purpose of this volume is to provide a synopsis of present knowledge of the structure, organisation, and function of cellular organelles with an emphasis on the examination of important but unsolved problems, and the directions in which molecular and cell biology are moving. Though designed primarily to meet the needs of the first-year medical student, particularly in schools where the traditional curriculum has been partly or wholly replaced by a multi-disciplinary core curriculum, the mass of information made available here should prove useful to students of biochemistry, physiology, biology, bioengineering, dentistry, and nursing. It is not yet possible to give a complete account of the relations between the organelles of two compartments and of the mechanisms by which some degree of order is maintained in the cell as a whole. However, a new breed of scientists, known as molecular cell biologists, have already contributed in some measure to our understanding of several biological phenomena notably interorganelle communication. Take, for example, intracellular membrane transport: it can now be expressed in terms of the sorting, targeting, and transport of protein from the endoplasmic reticulum to another compartment. This volume contains the first ten chapters on the subject of organelles. The remaining four are in Volume 3, to which sections on organelle disorders and the extracellular matrix have been added.

Abstracts

Abstracts PDF Author: C. Fred Fox
Publisher:
ISBN:
Category : Molecular biology
Languages : en
Pages : 349

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Origin and Continuity of Cell Organelles

Origin and Continuity of Cell Organelles PDF Author: J. Reinert
Publisher: Springer Science & Business Media
ISBN: 3540363963
Category : Science
Languages : en
Pages : 342

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Book Description
The first volume of the series, on "The Stability of the Differentiated State" received many favorable reviews from the scientific community. Many readers seem to agree with us that publication of topical volumes is a worthwhile alternative to periodic compilations of rather unrelated, though up-to-date reviews. Production of topical volumes is however, plagued with one great difficulty, that of "author synchronization". This difficulty explains the lag between volumes 1 and 2 of the series. Nevertheless we hope that the present volume will be appreciated as a valuable source of information on its central topic: How do cell organelles originate, and what mechanisms assure their continuity? Tübingen, Berlin, Zürich, \V. BEERMANN, J. REINERT, H. URSPRUNG, Heidelberg H. -W. HA GENS Contents Assembly, Continuity, and Exchanges in Certain Cytoplasmic Membrane Systems by W. GORDON WHALEY, MARIANNE DAUWALDER, aüd ]OYCE E. KEPHART 1 I. The Nature of the Membrane. . . . . . H. The Assembly of Membranes . . . . . . 5 III. The Growth and Transfer of Membranes. 6 A. The Nuclear Envelopc . . . 6 B. The Endoplasmic Reticulum 13 C. The Golgi Apparatus . 17 D. The Plasma Membrane 28 E. Vacuoles and Vesicles 31 IV. Concluding Remarks 37 References . . . . . 38 Origin and Continuity of Mitochondria by ROBERT BAXTER 1. Introduction . . . . . . . . . . . . . 46 H. Mitochondrial Biogenesis : thc Machincry 46 III. Limitations of Mitochondrial Autonomy 50 IV. The Replication of Mitochondria 53 V. Discussion and Conclusion 58 Referenccs . . . . . . . . . 59 Origin and Continuity of Plastids by \VILFRIED STUBBE 1. Introduction . . . . . . . . . . . . . 65 II. Arguments for the Continuity of Plastids .

Focus on Multidimensional Microscopy

Focus on Multidimensional Microscopy PDF Author: P C Cheng
Publisher: World Scientific
ISBN: 981449772X
Category : Science
Languages : en
Pages : 660

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Book Description
This book covers various aspects of modern microscopy, with emphasis on multidimensional (three-dimensional and higher) and multimodality microscopy. The topics discussed include multiphoton fluorescent microscopy, confocal microscopy, x-ray microscopy and microtomography, electron microscopy, probe microscopy and multidimensional image processing for microscopy. In addition, there are chapters demonstrating typical microscopical applications, both biological and material. Contents: Fluorescence Lifetime Imaging by Double Pulse Excitation in Bilateral Confocal Microscopy (G J Brakenhoff et al.)Icosahedral Virus Structure Determination by Electron Cryomicroscopy: Image Processing Principles (P A Thuman-Commike & W Chiu)Appropriate Image Processing for Confocal Microscopy (G Cox & C J R Sheppard)X-Ray Fluorescence Two-Dimensional Microanalysis at the VEPP-3 Storage Ring: Applications in Environmental Science (I P Dolbnya & K V Zolotarev)3D Transfer-Function Analysis for 4Pi Confocal Microscopy (M Gu & C J R Sheppard)Image Restoration of Thick Biological Specimens for Transmission Electron Microscope Tomography (K F Han et al.)Images of Membrane-Bound Detoxification Enzyme at 4Å Resolution Obtained by Electron Cryomicroscopy (I Schmidt-Krey et al.)The Uptake Pathway of DNA and Lipids in Cationic Liposome-Mediated Gene Transfer (S-W Hui et al.)Multiscale Imaging, Analysis and Modeling of the Pulmonary Bronchial Tree (A Kriete et al.)Asymmetric Cell Division as a Mechanism of Cell Determination in Vascular Plants (B-L Lin)3D Electron Microscopy of Cells and Organelles by High-Voltage EM, Tomography and Stereopair Analysis (M Marko)Surface Scattering Techniques in Scanning Optical Microscopy (J F Aguilar & E R Méndez)Applications of Electron Microscopy to Materials and Earth Sciences – Dislocation, Shape and Orientation Changes and Interdiffusion (P Shen)Surface Profiling and Confocal Microscopy (C J R Sheppard & J C Quartel)Matched Spatial Filters in Long Working Distance Microscopy of Phase Objects (J R Strickler & J-S Hwang)Transport Pathways of Lipoproteins Across the Arterial Endothelial Cells (C-H Kao et al.)Polarisation Effects in Confocal Microscopy (T Wilson)Near-Field Microscopy and Spectroscopy of Single Molecules, Single Proteins and Biological Membranes (X S Xie et al.) Keywords:Microscopy;Optics;Image Processing

The Journal of Cell Biology

The Journal of Cell Biology PDF Author:
Publisher:
ISBN:
Category : Cells
Languages : en
Pages :

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Book Description
No. 2, pt. 2 of November issue each year from v. 19-47; 1963-70 and v. 55- 1972- contain the Abstracts of papers presented at the annual meeting of the American Society for Cell Biology, 3d-10th; 1963-70 and 12th- 1972- .

Nasal Tumors in Animals and Man Vol. II (1983)

Nasal Tumors in Animals and Man Vol. II (1983) PDF Author: Gerd Reznik
Publisher: CRC Press
ISBN: 1351359916
Category : Medical
Languages : en
Pages : 282

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Book Description
This Monograph brings together within one cover the current knowledge about tumors of the nasal passages in man, in domestic and nondomestic animals, and in the rodents which are commonly employed in carcinogenesis studies in the laboratory.

Anatomy and Physiology Volume 2 of 3

Anatomy and Physiology Volume 2 of 3 PDF Author: Textbook Equity Edition
Publisher: Lulu.com
ISBN: 1304840026
Category :
Languages : en
Pages :

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Tumors of the Central Nervous System, Volume 2

Tumors of the Central Nervous System, Volume 2 PDF Author: M.A. Hayat
Publisher: Springer Science & Business Media
ISBN: 9789400706187
Category : Medical
Languages : en
Pages : 458

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Book Description
Advantages and limitations of biomarkers in gliomagenesis are described. Molecular subtypes of gliomas are detailed. The role played by TP53 gene mutation in the deadliest brain tumor, glioblastoma multiforme, is pointed out. The role of mutations of IDH1 and IDH2, and isocitrate dehydrogenases in malignant gliomas are presented. Metabolic differences in different regions of the glioma tumor are clarified. Various types of imaging modalities, including PET and SPECT, to diagnose gliomas in general and glioblastoma in particular in patients are explained in detail. Both low-grade and high-grade gliomas are discussed. Conventional as well as fluorescent-guided resection techniques for high-grade, recurrent malignant gliomas are detailed. Impact of resection extent on outcomes in patients with high-grade gliomas is clarified. The advantage of the use of intraoperative low-field MRI in glioma surgery is explained.